Buy reliable Quality 18-HYDROXY-11-DEOXYCORTICOSTERONE 379-68-0 raw material with Honest Price

Q: What is the 18-HYDROXY-11-DEOXYCORTICOSTERONE?

18-HYDROXY-11-DEOXYCORTICOSTERONE is , while it's Molecular Formula is C21H30O4. 11-Deoxy-18-hydroxycorticosterone is an analog of Corticosterone (C695700); a glucocorticoid and intermediate in the biosynthesis of Aldosterone (A514700) which is an adrenocortical steroid isolated from the adrenal cortex.

Buy reliable Quality 18-HYDROXY-11-DEOXYCORTICOSTERONE 379-68-0 raw material with Honest Price We provide high quality 18-HYDROXY-11-DEOXYCORTICOSTERONE (CAS 379-68-0), at a very affordable prices to our customers.

1.What is the 18-HYDROXY-11-DEOXYCORTICOSTERONE ?

18-hydroxy-11-deoxy Corticosterone (18-OH-DOC) is a mineralocorticoid secreted by the zona fasciculata of the adrenal gland. Its biosynthesis is regulated by adrenocorticotropic hormone (ACTH; ) as well as angiotensin II , which increases 18-OH-DOC production in isolated human adrenal glomerulosa cells. 18-OH-DOC can be formed via conversion of 11-deoxy corticosterone (DOC; ) in human SK-MEL188 melanoma cells. 18-OH-DOC is an intermediate in the metabolism of progesterone and can be converted to aldosterone by the capsular portion of rat adrenal glands. Continuous infusion of 18-OH-DOC (200 μg/rat per day) increases systolic blood pressure in uninephrectomized saline-drinking rats. Plasma levels of 18-OH-DOC are elevated in a db/db mouse model of type 2 diabetes.

11-Deoxy-18-hydroxycorticosterone is an analog of Corticosterone (C695700); a glucocorticoid and intermediate in the biosynthesis of Aldosterone (A514700) which is an adrenocortical steroid isolated from the adrenal cortex.

2.What is the CAS number for 18-HYDROXY-11-DEOXYCORTICOSTERONE ?

The CAS number of 18-HYDROXY-11-DEOXYCORTICOSTERONE is 379-68-0.

More information of 18-HYDROXY-11-DEOXYCORTICOSTERONE 379-68-0 are:

CAS?Number	379-68-0
Density	1.22 g/cm³
Melting Point	171-173 °C
Boiling Point	535.4 °C at 760 mmHg
Flash Point	291.7 °C
Vapor Pressure	1.06E-13mmHg at 25°C
Refractive Index	1.577
PSA	74.60000
LogP	2.66830

3.What is the molecular formula of 18-HYDROXY-11-DEOXYCORTICOSTERONE ?

The chemical formula of?18-HYDROXY-11-DEOXYCORTICOSTERONE is C21H30O4 which containing 21 Carbon atoms,30 Hydrogen atoms and 4 Oxygen atoms,and the molecular weight, and the molecular weight of 18-HYDROXY-11-DEOXYCORTICOSTERONE is 346.467

4.What is 18-HYDROXY-11-DEOXYCORTICOSTERONE(379-68-0)used for?

18-hydroxy-11-deoxy Corticosterone (18-OH-DOC) is a mineralocorticoid secreted by the zona fasciculata of the adrenal gland. Its biosynthesis is regulated by adrenocorticotropic hormone (ACTH; ) as well as angiotensin II , which increases 18-OH-DOC production in isolated human adrenal glomerulosa cells. 18-OH-DOC can be formed via conversion of 11-deoxy corticosterone (DOC; ) in human SK-MEL188 melanoma cells. 18-OH-DOC is an intermediate in the metabolism of progesterone and can be converted to aldosterone by the capsular portion of rat adrenal glands. Continuous infusion of 18-OH-DOC (200 μg/rat per day) increases systolic blood pressure in uninephrectomized saline-drinking rats. Plasma levels of 18-OH-DOC are elevated in a db/db mouse model of type 2 diabetes.

InChI:InChI=1/C21H30O4/c1-20-8-6-14(24)10-13(20)2-3-15-16(20)7-9-21(12-23)17(15)4-5-18(21)19(25)11-22/h10,15-18,22-23H,2-9,11-12H2,1H3/t15-,16+,17+,18-,20+,21-/m1/s1

Relevant articles related to 18-HYDROXY-11-DEOXYCORTICOSTERONE:

Article

Source

Inhibition of aldosterone formation by cortisol in rat adrenal mitochondria

Matkovic, Laura,Gomez-Sanchez, Celso E.,Lantos, Carlos P.,Cozza, Eduardo N.

, p. 447 - 452 (1995)

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