- Product Name 3-(Trifluoromethyl)benzoic acid
- cas 454-92-2
- purity 99%
Agrochemicals
3-(Trifluoromethyl)benzoic acid
Manufacturer supply 3-(Trifluoromethyl)benzoic acid 454-92-2 with sufficient stock and high standard
- Molecular Formula: C8H5F3O2
- Molecular Weight: 190.122
- Appearance/Colour: white to light yellow crystal powder
- Vapor Pressure: 0.0241mmHg at 25°C
- Melting Point: 104-106 °C(lit.)
- Boiling Point: 237.7 °C at 760 mmHg
- PKA: 3.77±0.10(Predicted)
- Flash Point: 102.9 °C
- PSA： 37.30000
- Density: 1.403 g/cm3
- LogP: 2.40360
3-(Trifluoromethyl)benzoic acid(Cas 454-92-2) Usage
|
Definition |
ChEBI: A benzoic acid carrying a trifluoromethyl substituent at the 3-position. |
|
General Description |
pKa values of 3-(trifluoromethyl)benzoic acid in water and in methanol has been measured. Solubility of 3-(trifluoromethyl)benzoic acid in dense carbon dioxide was evaluated to investigate the influence of fluorination on the solubility of organic pharmaceuticals in dense carbon dioxide. |
InChI:InChI=1/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13)/p-1
454-92-2 Relevant articles
Aerobic oxidation of aldehydes to carboxylic acids catalyzed by recyclable ag/c3 n4 catalyst
Wu, Chaolong,Yao, Xiaoquan,Yu, Min,Zhou, Li,Zhu, Li
, p. 167 - 175 (2021/03/19)
The oxidation of aldehydes is an efficie...
Synthesis and structure-activity relationships of new 2-phenoxybenzamides with antiplasmodial activity
Dolensky, Johanna,Hermann, Theresa,Hochegger, Patrick,Kaiser, Marcel,M?ser, Pascal,Pferschy-Wenzig, Eva-Maria,Saf, Robert,Seebacher, Werner,Weis, Robert
, (2021/11/08)
The 2-phenoxybenzamide 1 from the Medici...
Hydrolysis of amides to carboxylic acids catalyzed by Nb2O5
Siddiki,Rashed, Md. Nurnobi,Touchy, Abeda Sultana,Jamil, Md. A. R.,Jing, Yuan,Toyao, Takashi,Maeno, Zen,Shimizu, Ken-Ichi
, p. 1949 - 1960 (2021/03/26)
Hydrolysis of amides to carboxylic acids...
Cobalt-catalyzed carboxylation of aryl and vinyl chlorides with CO2
Wang, Yanwei,Jiang, Xiaomei,Wang, Baiquan
supporting information, p. 14416 - 14419 (2020/12/01)
The transition-metal-catalyzed carboxyla...
454-92-2 Process route
-
-
402-31-3
1,3-bis(trifluoromethyl)benzene
-
-
454-92-2
3-(trifluoromethyl)benzoic acid
-
-
328-73-4
3,5-bis(trifluoromethyl)iodobenzene
Conditions
| Conditions | Yield |
|---|---|
|
With
sulfuric acid; iodine;
for 7h;
Ambient temperature;
|
70%
8% |
-
-
124-38-9,18923-20-1
carbon dioxide
-
-
98-08-8
α,α,α-trifluorotoluene
-
-
454-92-2
3-(trifluoromethyl)benzoic acid
-
-
455-24-3
4-trifluoromethylbenzoic acid
-
-
433-97-6
2-trifluoromethylbenzoic acid
Conditions
| Conditions | Yield |
|---|---|
|
With
2,2,6,6-tetramethylpiperidinyl-lithium;
In
tetrahydrofuran;
at -75 ℃;
for 2h;
|
|
|
With
LIS-PMDTA;
In
tetrahydrofuran;
at -75 ℃;
for 10h;
|
454-92-2 Upstream products
-
109-72-8
n-butyllithium
-
60-29-7
diethyl ether
-
98-08-8
α,α,α-trifluorotoluene
-
368-77-4
3-trifluoromethylbenzonitrile
454-92-2 Downstream products
-
328-80-3
3-nitro-5-trifluoromethyl-benzoic acid
-
2251-65-2
3-(Trifluoromethyl)benzoyl chloride
-
2557-13-3
3-trifluoromethylbenzoic acid methyl ester
-
142056-94-8
Methyl-3-trifluormethyl-cyclohexan-1-carboxylat
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