99% Purity Commercial production Broxuridine 59-14-3 with Cheapest Price

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Broxuridine

Product Name Broxuridine
cas 59-14-3
purity 99%

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99% Purity Commercial production Broxuridine 59-14-3 with Cheapest Price We supply high quality Broxuridine (CAS 59-14-3), in stock, factory directly supply to clients, lower prices, more competitiveness.

What is the Broxuridine ?

Broxuridine is white crystalline powder, while it's Molecular Formula is C9H11BrN2O5. 5-Bromo-2'-deoxyuridine (BrdU) is a thymidine analog used to label DNA. It is incorporated into newly synthesized DNA in place of thymidine during the S phase of the cell cycle. Cells that were actively proliferating can then be detected by denaturing the DNA and allowing specific antibodies to target the BrdU incorporation. Consequently 5-BrdU is used to study cell signaling and other processes that induce cell proliferation.

What is the CAS number for Broxuridine ?

The CAS number of Broxuridine is 59-14-3.

More information of Broxuridine 59-14-3 are:

Synonyms	(+)-5-Bromo-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione;2'-Deoxy-5-bromouridine;5-Bromo-2'-desoxyuridine;5-Bromodeoxyuridine;5-Bromouracil deoxyriboside;5-Bromouracil-2-deoxyriboside;BRUDR;BUdR;Bromodeoxyuridine;NSC 38297;
CAS?Number	59-14-3
Molecular Formula	C9H11BrN2O5
Molecular Weight	307.101
Density	1.905 g/cm³
Melting Point	191-194 °C (dec.)(lit.)
HS CODE	29349990
PSA	104.55000
LogP	-1.06020
Pka	7.73±0.10(Predicted)

What is Broxuridine (59-14-3) used for?

5-Bromo-2'-deoxyuridine is a nitrate reductase inhibitor that prevents the reduction of nitrate to nitrite by inhibiting the enzyme nitrate reductase. 5-Bromo-2'-deoxyuridine is a genotoxic agent that has been shown to cause DNA damage and cell death in vitro. 5-Bromo-2'-deoxyuridine also binds to NMDA receptors and may be useful as a model system for studying neurodegenerative diseases.

Articles related to Broxuridine:

Article

Source

Thermodynamic Reaction Control of Nucleoside Phosphorolysis

Kaspar, Felix,Giessmann, Robert T.,Neubauer, Peter,Wagner, Anke,Gimpel, Matthias

supporting information, p. 867 - 876 (2020/01/24)

Biotransformation of halogenated nucleosides by immobilized Lactobacillus animalis 2′-N-deoxyribosyltransferase

Britos, Claudia N.,Lapponi, María José,Cappa, Valeria A.,Rivero, Cintia W.,Trelles, Jorge A.

, p. 91 - 96 (2016/05/10)

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